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Found 4 of ec50 data for polymerid = 1996,50002335,50007090
TargetHistone deacetylase 8(Homo sapiens (Human))
S£O Paulo State University (Unesp)

Curated by ChEMBL
LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)
Affinity DataEC50:  216nMAssay Description:Inhibition of recombinant human HDAC8 expressed in baculovirus expression system using FDL as substrate incubated for 3 hrs by by fluorescence-based ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
S£O Paulo State University (Unesp)

Curated by ChEMBL
LigandPNGBDBM32203(8-quinolinol | CHEMBL310555 | US10005735, Table 1....)
Affinity DataEC50:  1.11E+4nMAssay Description:Substrate-dependent activation of HDAC8 (unknown origin) using FLUOR DE LYS as substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
S£O Paulo State University (Unesp)

Curated by ChEMBL
LigandPNGBDBM50239391(2-Mercapto-Benzoic Acid | CHEBI:59124 | THIOSALICY...)
Affinity DataEC50:  1.69E+4nMAssay Description:Substrate-dependent activation of HDAC8 (unknown origin) using FLUOR DE LYS as substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
S£O Paulo State University (Unesp)

Curated by ChEMBL
LigandPNGBDBM50465051(CHEMBL4285950)
Affinity DataEC50:  3.41E+5nMAssay Description:Inhibition of human HDAC8 using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed